Marvin M. Lipman, M.D. tells about a disappointed
patient, a 50-year old stockbroker who came to see him with a four-day history
of a sore throat, coughing, postnasal drip and low-grade fever. He said his previous physician had always
given him a Z-Pak (a five-day course of antibiotic azithromycin) for similar
symptoms and he always got better. I
explained that it was more likely that he had a viral infection for which an
antibiotic would be useless. I outlined
some over-the-counter drugs that might be of help. He left the office in a huff and I never saw
him again.
The age of antibiotics began in the 1930s
with the introduction of sulfa drugs followed by penicillin in 1941. During the last century, antibiotics saved
the lives of countless millions of people infected with the deadly
bacteria. The war against viruses, with
a few notable exceptions, has not been as successful. Physicians began writing antibiotic
prescriptions “just in case” bacteria might also be involved. Patients came to expect and even demand such
treatment. Unnecessary antibiotics not
only exposes patients to harmful side effects, such as debilitating diarrhea,
but also led directly to the emergence of resistant strains of bacteria that then
went on to infect others.
Untreated sore throats can appease
miserable patients desperate for a quick cure, but the practice dates back to a
time when untreated sore throats were followed by rheumatic fever or acute
kidney disease. Strep throat accounted
for only 5 to 15 percent of all sore throats.
Today, there is no need to give antibiotics “just in case” it is
strep. The organism can be reliably
detected with a simple throat swab, with results available within 24
hours. The disease can almost always be
distinguished from a viral sore throat on clinical grounds alone. The patient is usually less than 50 years of
age and the sore throat can come on quickly within hours or overnight, making
swallowing so difficult that drooling can occur. The breath has a foul odor, and even speech
is affected and a temperature of over 101 degrees F., accompanied by chilly
sensations. One can easily notice tender
swollen lymph nodes under the jaw, and yellowish pus overlying the
tonsils. A strep evidently lacks the ingenuity
to have developed resistance so penicillin is still the mainstay of treatment
unless one is allergic to it. Throat
lozenges, gargling with warm salt water and of course the good old chicken soup
treatment would have helped my stockbroker more.
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